Engler JA, Kay MA: A direct comparison of two nonviral gene

Ohlfest JR, Frandsen JL, Fritz S, Lobitz PD, Perkinson SG, Clark KJ, Nelsestuen G, Crucial NS, McIvor RS, Hackett PB, Largaespada DA: Phenotypic correction and E widely distributed in the genome, when transposition occurs from a long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer working with the Sleeping Beauty transposon technique. Mol Ther 2005, 12:778?88. 19. Ohlfest JR, Lobitz PD, Perkinson SG, Largaespada DA: Integration and long-term expression in xenografted human glioblastoma cells working with a plasmid-based transposon technique. Mol Ther 2004, ten:260?68. 20. Prak ET, Kazazian HH Jr: Mobile components and title= SART.S23506 the human genome. Nat Rev Genet 2000, 1:134?44. 21. Smit AF: Interspersed repeats and other mementos of transposable elements in mammalian genomes.Engler JA, Kay MA: A direct comparison of two nonviral gene therapy vectors for somatic integration: in vivo evaluation with the bacteriophage integrase title= fpsyg.2016.00135 phiC31 along with the Sleeping Beauty transposase. Mol Ther 2005, 11:695?06. 7. Mikkelsen JG, Yant SR, Meuse L, Huang Z, Xu H, Kay MA: HelperIndependent Sleeping Beauty transposon-transposase vectors for efficient nonviral gene delivery and persistent gene expression in vivo. Mol Ther 2003, eight:654?65. eight. Ohlfest JR, Frandsen JL, Fritz S, Lobitz PD, Perkinson SG, Clark KJ, Nelsestuen G, Key NS, McIvor RS, Hackett PB, Largaespada DA: Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer working with the Sleeping Beauty transposon technique. Blood 2005, 105:2691?698. 9. Yant SR, Kay MA: Nonhomologous-end-joining aspects regulate DNA repair fidelity in the course of Sleeping Beauty element transposition in mammalian cells. Mol Cell Biol 2003, 23:8505?518. ten. Aronovich EL, Bell JB, Khan SA, Belur LR, Gunther R, Koniar B, Schachern PA, Parker JB, Carlson CS, Whitley CB, et al: Systemic correction of storage disease in MPS I NOD/SCID mice making use of the sleeping beauty transposon technique. Mol Ther 2009, 17:1136?144. 11. Belur LR, Frandsen JL, Dupuy AJ, Ingbar DH, Largaespada DA, Hackett PB, Scott McIvor R: Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon method. Mol Ther 2003, eight:501?07. 12. Liu L, Sanz S, Heggestad AD, Antharam V, Notterpek L, Fletcher BS: Endothelial targeting in the Sleeping Beauty transposon inside lung. Mol Ther 2004, 10:97?05. 13. Liu H, Liu L, Fletcher BS, Visner GA: Sleeping Beauty-based gene therapy with indoleamine two,3-dioxygenase inhibits lung allograft fibrosis. Faseb J 2006, 20:2384?386. 14. Belur LR, Podetz-Pedersen K, Frandsen J, McIvor RS: Lung-directed gene therapy in mice applying the nonviral Sleeping Beauty transposon technique. Nat Protoc 2007, 2:3146?152. 15. Lin EH, Keramidas M, Rome C, Chiu WT, Wu CW, Coll JL, Deng WP: Lifelong reporter gene imaging inside the lungs of mice following polyethyleneimine-mediated sleeping-beauty transposon delivery. Biomaterials 2011, 32:1978?985.16. Liu L, Mah C, Fletcher BS: Sustained FVIII expression and phenotypic correction of hemophilia A in neonatal mice utilizing an endothelialtargeted sleeping beauty transposon. Mol Ther 2006, 13:1006?015. 17. Ortiz-Urda S, Lin Q, Yant SR, Keene D, Kay MA, Khavari PA: Sustainable correction of junctional epidermolysis bullosa by means of transposon-mediated nonviral gene transfer.

Last modified on 10 December 2017, at 09:41